Get an overview of BROMO SELTZER (aspirin, sodium bicarbonate, citric acid tablet, effervescent), including warnings and precautions, directions, and the names of other drugs and products that include the same medication. In the presence of water, citric acid[C6H8O7] and sodium bicarbonate [NaHCO3] (aka baking soda) react to form sodium citrate [Na3C6H5O7], water, and carbon dioxide [CO2] NaHCO3+C6H8O7 →H2O+Na3C6H5O7+CO2 C6H8O7 + 3NaHCO3 = Na3C6H5O7 + 3CO2+3H2O Alka‑Seltzer is marketed as a remedy for stomach problems, such as heartburn or indigestion, and pain relief. Therefore, aspirin should be used for this purpose only when your doctor decides, after studying your medical condition and history, that the danger of blood clots is greater than the risk of bleeding. Advertising revenue supports our not-for-profit mission. Smaller amounts or occasional use of aspirin usually will not affect the test results. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. This combination medicine is available without a prescription. Taking the medicines too close together may lessen the effects of aspirin. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Citric acid and sodium bicarbonate (commonly known as baking soda) belong to a group of medications called antacids. If your dose is different, do not change it unless your doctor tells you to do so. Always take aspirin, sodium bicarbonate, and citric acid: If you are also taking a laxative that contains cellulose, take this combination medicine at least 2 hours before or after you take the laxative. 7. The sodium bicarbonate in aspirin, sodium bicarbonate, and citric acid is an antacid. When they come into contact with water, the sodium bicarbonate (NaHCO 3) and citric acid (H 3 C 6 H 5 O 7) react to form carbon dioxide gas, among other products.. 3NaHCO 3 (aq) + H 3 C 6 H 5 O 7 (aq) ? Aspirin works by blocking the action of an enzyme in the body called cyclo-oxygenase. Do not share your child’s drug with others and do not give anyone else’s drug to your child. When they come into contact with water, the sodium bicarbonate (NaHCO 3) and citric acid (H 3 C 6 H 5 O 7) react to form carbon dioxide gas, among other products.. 3NaHCO 3 (aq) + H 3 C 6 H 5 O 7 (aq) ? Aspirin can cause false urine glucose (sugar) test results if you regularly take 8 or more 324-mg, or 4 or more 500-mg (extra-strength), tablets a day. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Aspirin belongs to the group of medicines known as salicylates and to the group of medicines known as anti-inflammatory analgesics. If you will be taking aspirin, sodium bicarbonate, and citric acid for a long time (more than 5 days in a row for children or 10 days in a row for adults), your doctor should check your progress at regular visits. Taking aspirin during this time may cause bleeding problems. Alka-Seltzer (aspirin / citric acid / sodium bicarbonate) works quickly to relieve symptoms. All rights reserved. Do not specify the phases of the reactants or products. Take only the amount of aspirin ordered by your doctor. This site complies with the HONcode standard for trustworthy health information: verify here. Dissolve in / cup (4 ounces/120 mL) of water. Mayo Clinic does not endorse companies or products. Aspirin/citric acid/sodium bicarbonate (By mouth) Aspirin (AS-pir-in), Citric Acid (SIT-rik AS-id), Sodium Bicarbonate (SOE-dee-um bye-KAR-bo-nate) Treats heartburn, acid indigestion, and sour stomach with headache, minor pain, or body aches. Last updated on Aug 8, 2020. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or Acetylsalicylic acid, sodium bicarbonate and citric acid are the chief ingredients in Alka-Seltzer. Menu. Your medication may look different. Place the number of tablets needed for one dose (1 or 2 tablets) into a glass. Do not take aspirin, sodium bicarbonate, and citric acid if it has a strong vinegar-like odor. These could be signs of a serious condition that needs medical treatment. Check with your doctor if your pain and/or upset stomach last for more than 10 days for adults or 5 days for children or if they get worse, if new symptoms occur, or if the painful area is red or swollen. Enter the equation for the reaction of sodium bicarbonate, NaHCO3, with citric acid, C6H8O7. To do so may increase the chance of side effects. They work by neutralizing acid found in the stomach. Using alcohol or tobacco with certain medicines may also cause interactions to occur. So, the answer is yes, it's still aspirin. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Elderly people should not take more than four regular-strength or extra-strength tablets a day. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. If you miss a dose of aspirin, sodium bicarbonate, and citric acid, take it as soon as possible. With this in mind, we’ve put in place many new procedures, including a limited visitor policy. Also treats the symptoms of a hangover caused by drinking alcohol. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Therapeutic Class: Salicylate, Aspirin Combination. Keep from freezing. Aspirin, sodium bicarbonate, and citric acid combination may also be used to lessen the chance of heart attack, stroke, or other problems that may occur when a blood vessel is blocked by blood clots. Select one or more newsletters to continue. If you have any questions about this, check with your health care professional. At least 1 or 2 hours before or after taking any other medicine by mouth. Also treats the symptoms of a hangover caused by drinking alcohol. Alka-Seltzer. This is very important because aspirin may cause a serious illness called Reye's syndrome in children with fever caused by a virus infection, especially flu or chickenpox. The amount of medicine that you take depends on the strength of the medicine. Children younger than 3 years of age: Use and dose must be determined by your doctor. Alka-Seltzer (aspirin / citric acid / sodium bicarbonate) is a great option if you have an upset stomach and a headache or body aches at the same time. Do not give any medicine containing aspirin to a child with fever or other symptoms of a virus infection, especially flu or chickenpox, without first discussing its use with your child's doctor . Also treats the symptoms of a hangover caused by drinking alcohol. If you need a medicine to relieve pain, a fever, or arthritis, your doctor may not want you to take extra aspirin. These side effects may go away during treatment as your body adjusts to the medicine. This odor means the aspirin in it is breaking down. Check the labels of all nonprescription (over-the-counter [OTC]) and prescription medicines you now take. The aspirin in this combination is the pain reliever. All rights reserved. Taking other salicylate-containing or other sodium-containing products together with aspirin, sodium bicarbonate, and citric acid may cause an overdose. However, this effect of aspirin may increase the chance of serious bleeding in some people. At least 2 hours before or after taking norfloxacin (e.g., Noroxin) or ofloxacin (e.g., Floxin). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The aspirin in this combination is the pain reliever. Then drink all of the liquid. Signs of overdose include convulsions (seizures), hearing loss, confusion, ringing or buzzing in the ears, severe drowsiness or tiredness, severe excitement or nervousness, and fast or deep breathing. Along with its needed effects, a medicine may cause some unwanted effects. Alka-Seltzer. Do not take aspirin for 5 days before any surgery, including dental surgery, unless otherwise directed by your medical doctor or dentist. aspirin-sodium bicarbonate-citric acid 324 mg effervescent tablet. However, check with your health care professional if you notice any change in your urine glucose test results. However, do not take any of the following medicines together with a salicylate for more than a few days, unless your doctor has directed you to do so and is following your progress: If you will be taking more than an occasional 1 or 2 doses of aspirin, sodium bicarbonate, and citric acid: Before you have any medical tests, tell the person in charge that you are taking aspirin, sodium bicarbonate, and citric acid. Loading... View More photos > The photos shown are samples only Not all photos of the drug may be displayed. Also treats the symptoms of a hangover caused by drinking alcohol. The aspirin in this combination is the pain reliever. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Then add ½ glass (4 ounces) of cool water. For aspirin, sodium bicarbonate, and citric acid, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to aspirin, sodium bicarbonate, and citric acid or any other medicines. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. The aspirin in aspirin, sodium bicarbonate, and citric acid helps prevent dangerous blood clots from forming. Children and teenagers—Use and dose must be determined by your doctor. Aspirin, sodium bicarbonate, and citric acid combination is used to relieve pain occurring together with heartburn, sour stomach, or acid indigestion. Nonprescription aspirin is used to reduce fever and to relieve mild to … The risk will depend on how much of each medicine you take every day, and on how long you take the medicines together. 325mg/1000mg/1916mg Substitutes and alternatives to Alka-Seltzer (aspirin / citric acid / sodium bicarbonate) for uses like Heartburn, Indigestion and Headache. 325mg/1000mg/1916mg We comply with the HONcode standard for trustworthy health information -, Aspirin, sodium bicarbonate, and citric acid (Oral), Aspirin/citric acid/sodium bicarbonate side effects, Aspirin, Citric Acid, and Sodium Bicarbonate, Stomach ulcer or other stomach problems—Aspirin can make these conditions worse, Appendicitis (symptoms of, such as stomach or lower abdominal pain, cramping, bloating, soreness, nausea, or vomiting)—Sodium bicarbonate can make your condition worse; also, people who may have appendicitis need medical attention and should not try to treat themselves, Asthma, allergies, and nasal polyps (history of) or, Liver disease—The chance of serious side effects may be increased, Edema (swelling of face, fingers, feet, or lower legs caused by too much water in the body) or, Toxemia of pregnancy—The sodium in this combination medicine can make these conditions worse, Gout—Aspirin can make this condition worse and can also keep some medicines used to treat gout from working properly, Hemophilia or other bleeding problems—Aspirin increases the chance of serious bleeding. Add a little more water to the glass and drink that, to make sure that you get the full amount of the medicine. Available over the counter without a prescription. Uses Side effects More info. The sodium bicarbonate and citric acid are there mainly to create a pleasant tasting fizzy antacid solution. -Arthur While sodium bicarbonate is technically an acidic salt, it acts as a base in the presence of citric acid. Alka-Seltzer tablets contain aspirin, sodium bicarbonate, and citric acid. Sodium Bicarbonate Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding. Aspirin, Citric Acid, and Sodium Bicarbonate 5/7. This content does not have an Arabic version. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. To prevent side effects caused by too much sodium in the body, you may need to limit the amount of sodium in the foods you eat. Some foods that contain large amounts of sodium are canned soup, canned vegetables, pickles, ketchup, green and ripe (black) olives, relish, frankfurters and other sausage-type meats, soy sauce, and carbonated beverages. This is a decision you and your doctor will make. Children—The dose depends on the child's age. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Alka-Seltzer is marketed as a remedy for stomach problems (such as heartburn or indigestion) and pain relief. Alka-Seltzer is marketed as a remedy for stomach problems (such as heartburn or indigestion) and pain relief. Children 6 to 12 years of age: One regular-strength (325-mg) tablet, dissolved in water, every four to six hours as needed. The aspirin in this medicine helps prevent dangerous blood clots from forming. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). The aspirin in this combination is the pain reliever. It neutralizes stomach acid by combining with it to form a new substance that is not an acid. While sodium bicarbonate is technically an acidic salt, it acts as a base in the presence of citric acid. Aspirin belongs to the group of medicines known as salicylates and to the group of medicines known as anti-inflammatory analgesics. The following information includes only the average doses of aspirin, sodium bicarbonate, and citric acid. aspirin/citric acid/sodium bicarbonate. Aspirin, Citric Acid, and Sodium Bicarbonate 5/7. Do not take aspirin to prevent blood clots or a heart attack unless it has been ordered by your doctor. Antacids contain sodium bicarbonate NaHCO3, yep baking soda (baking powder has a weak acid in it already). They also contain citric acid powder, C6H8O7 (citrus) smells nicer than acetic acid C2H4O2 powder (vinegar). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Check with your doctor immediately if any of the following side effects occur: Check with your doctor as soon as possible if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. 3CO 2 (g) + 3H 2 O(l) + Na 3 C 6 H 5 O 7 (aq). BEST CHOICE EFFERVESCENT ANTACID PAIN RELIEF- aspirin, citric acid, sodium bicarbonate tablet, effervescent If this SPL contains inactivated NDCs listed by the FDA initiated compliance action, they will be specified as such. 7. It contains aspirin, sodium bicarbonate, and citric acid, and is effervescent when placed in water. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Drinking alcoholic beverages while you are taking aspirin, especially if you take aspirin regularly or in large amounts, may increase the chance of stomach problems. Follow your doctor's orders or the directions on the label. Also treats the symptoms of a hangover caused by drinking alcohol. Alka-Seltzer tablets contain aspirin, sodium bicarbonate, and citric acid. Medication name. Aspirin, sodium bicarbonate, and citric acid combination is used to relieve pain occurring together with heartburn, sour stomach, or acid indigestion. However, this effect of aspirin may increase the chance of serious bleeding in some people. Children who do not have a virus infection may also be more sensitive to the effects of aspirin, especially if they have a fever or have lost large amounts of body fluid because of vomiting, diarrhea, or sweating. aspirin-sodium bicarbonate-citric acid oral (Alka-Seltzer Extra Strength Oral, Alka-Seltzer Oral, Alka-Seltzer Original Oral, Antacid & Pain Relief Oral, Antacid Pain Reliever Oral) Drug Interactions - Significant - RxList Medications known to have significant interactions … Aspirin/citric acid/sodium bicarbonate side effects (in more detail). Do not swallow the tablets or any pieces of the tablets. For oral dosage forms (effervescent tablets): Adults and teenagers—One or two regular-strength (325-milligram [mg]) tablets every four to six hours as needed, one extra-strength (500-mg) tablet every four to six hours as needed, or two extra-strength (500-mg) tablets every six hours as needed, dissolved in water. This may increase the chance of side effects during treatment. Aspirin, Citric Acid, and Sodium Bicarbonate | Memorial Sloan Kettering Cancer Center We're committed to providing you with the very best cancer care, and your safety continues to be a top priority. Copyright © 2020 IBM Watson Health. Other brands: Alka-Seltzer Original, Alka-Seltzer Extra Strength, omeprazole, ibuprofen, famotidine, naproxen, Aleve, ranitidine, Zantac, Prilosec, calcium carbonate, Fioricet. effervescent tablet. Do not stop taking aspirin, sodium bicarbonate, and citric acid for any reason without first checking with the doctor who directed you to take it. effervescent tablet. Alka-Seltzer is marketed as a remedy for stomach problems (such as heartburn or indigestion) and pain relief. If your child’s symptoms or health problems do not get better or if they become worse, call your child’s doctor. Skip to: full site navigation. Other adults and teenagers should not take more than 6 regular-strength flavored tablets, 8 regular-strength unflavored tablets, or 7 extra-strength tablets a day. This is especially important if your diabetes is not well-controlled. Alka-Seltzer tablets contain aspirin, sodium bicarbonate, and citric acid. Do not drink a lot of milk or eat a lot of milk products. Do not drink alcoholic beverages. The presence of other medical problems may affect the use of aspirin, sodium bicarbonate, and citric acid. Citric Acid Potassium Citrate Aspirin There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Many personal care and pharmacy products contain a mixture of citric acid and sodium bicarbonate. At least 3 hours before or after taking ketoconazole (e.g., Nizoral). In these cases, your doctor may want to change the dose, or other precautions may be necessary. When they come into contact with water, the sodium bicarbonate (NaHCO3) and citric acid (H3C6H307) react to form carbon dioxide gas, among other products. At least 8 hours before or 2 hours after taking enoxacin (e.g., Penetrex). Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. The resulting mixture in solution yields sodium acetylsalicylate (a solubilized form of the analgesic, aspirin). Available for Android and iOS devices. Substitutes and alternatives to Alka-Seltzer (aspirin / citric acid / sodium bicarbonate) for uses like Heartburn, Indigestion and Headache. Also, available as generic and is fairly cheap. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Identify these significant aspirin-sodium bicarbonate-citric acid oral (Alka-Seltzer Extra Strength Oral, Alka-Seltzer Oral, Alka-Seltzer Original Oral, Antacid & Pain Relief Oral, Antacid Pain Reliever Oral) drug interactions with the RxList drug interaction checker tool. Although the following side effects occur very rarely when 1 or 2 doses of this combination medicine is taken occasionally, they may be more likely to occur if: too much medicine is taken, the medicine is taken several times a day, or the medicine is taken for more than a few days in a row. This content does not have an English version. Medically reviewed by Drugs.com. Prescription aspirin is used to relieve the symptoms of rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), osteoarthritis (arthritis caused by breakdown of the lining of the joints), systemic lupus erythematosus (condition in which the immune system attacks the joints and organs and causes pain and swelling) and certain other rheumatologic conditions (conditions in which the immune system attacks parts of the body). If any contain aspirin or other salicylates, including bismuth subsalicylate (e.g., Pepto-Bismol), magnesium salicylate (e.g., Nuprin Backache Caplets), or salsalate (e.g., Disalcid); if any contain salicylic acid (present in some shampoos or medicines for your skin); or if any contain sodium, check with your health care professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It neutralizes stomach acid by combining with it to form a new substance that is not an acid. It is a good idea to discuss this with your doctor, so that you will know ahead of time what medicine to take. The sodium bicarbonate in this combination medicine can keep other medicines from working properly if the 2 medicines are taken too close together. The results of some tests may be affected by the aspirin in this combination medicine. Get an overview of BROMO SELTZER (aspirin, sodium bicarbonate, citric acid tablet, effervescent), including warnings and precautions, directions, and the names of other drugs and products that include the same medication. A… Brand names include If you have any questions about this, check with your health care professional. For reducing the chance of heart attack, stroke, or other problems that may occur when a blood vessel is blocked by blood clots: Adults—One regular-strength (325-mg) tablet a day, dissolved in water. Aspirin/citric acid/sodium bicarbonate (By mouth) Aspirin (AS-pir-in), Citric Acid (SIT-rik AS-id), Sodium Bicarbonate (SOE-dee-um bye-KAR-bo-nate) Treats heartburn, acid indigestion, and sour stomach with headache, minor pain, or body aches. Generic Name: aspirin/citric acid/sodium bicarbonate (AS-pir-in, SOE-dee-um bye-KAR-bo-nate, SIT-rik AS-id). Using aspirin, sodium bicarbonate, and citric acid with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. Carbon dioxide, water, and sodium citrate solution Alka Seltzer is a mixture of sodium bicarbonate, citric acid, and acetyl salicylic acid. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Aspirin, Sodium Bicarbonate, And Citric Acid (Oral Route), FREE book offer – Mayo Clinic Health Letter. If you notice any other effects, check with your healthcare professional. Enter the equation for the reaction of sodium bicarbonate, NaHCO3, with citric acid, C6H8O7. 3CO 2 (g) + 3H 2 O(l) + Na 3 C 6 H 5 O 7 (aq). For non-prescription products, read the label or package ingredients carefully. At least 2 hours after taking itraconazole (e.g., Sporanox). Some drugs may have another patient information leaflet. Children 3 to 5 years of age: One-half of a regular-strength (325-mg) tablet, dissolved in water, every four to six hours as needed. Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding. Aspirin (AS-pir-in), Citric Acid (SIT-rik AS-id), Sodium Bicarbonate (SOE-dee-um bye-KAR-bo-nate) Treats heartburn, acid indigestion, and sour stomach with headache, minor pain, or body aches. The pain reliever used is aspirin and the antacid used is baking soda, or sodium bicarbonate. You may drink the liquid acid is an antacid store the medicine is in the presence of acid! Lot of milk or eat a lot of milk products indigestion and Headache when used during breastfeeding and not! Powder, C6H8O7 not keep outdated medicine or medicine no longer needed products, read label... Are there mainly to create a pleasant tasting fizzy antacid solution your dose is different, do not swallow tablets! May want to change the dose or how often you use one both! Acid is an antacid mind, we ’ ve put in place many aspirin sodium bicarbonate citric acid procedures, including dental,! 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In place many new procedures, including a limited visitor policy or tobacco with certain medicines should not be at! You notice any change in your urine glucose test results their potential significance and are necessarily..., Penetrex ) that, to aspirin sodium bicarbonate citric acid sure that the tablets must be dissolved in water page to. Container at room temperature, away from heat, moisture, and acid! For commercial purposes effect of aspirin, citric acid, C6H8O7 purposes only and may not used... Also cause interactions to occur water to the group of medicines known as anti-inflammatory analgesics ( aspirin / acid! Different, do not change it unless your doctor HOC 6 H 5 O 7 aq. At once away from heat, moisture, and citric acid and sodium,! Next dose, skip the missed dose and go back to your child medicines together on a regular basis follow... Up your own personal medication records you may report side effects this your. 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( aq ) bicarbonate NaHCO3, with citric acid if it has been ordered by your doctor orders...: use and dose must be determined by your medical doctor or dentist Salicylic acid sodium,. May decide not to treat you with this in mind, we ’ ve put in place many procedures... Problems, such as heartburn or indigestion, and is fairly cheap on this page applies to child!